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Objective physiological data gathered from skin biopsies in this same study showed that after approximately six months of targeted supplementation with L-methylfolate, methylcobalamin, and pyridoxal 5'-phosphate, 73% of the patients demonstrated a measurable increase in calf epidermal nerve fiber density

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The most common neurological conditions we see that are linked to SIBO are Parkinsons disease, diabetes, traumatic brain injury, autonomic nervous system dysfunction like postural orthostatic tachycardia syndrome (PoTS) and dysautonomia, and very importantly, vagus nerve dysfunction